Key Takeaways
- Injectable GHK-Cu: 1–2mg per injection, once or twice daily
- Topical GHK-Cu cream/serum: 2–4% concentration, once or twice daily
- Cycle length: 8–12 weeks on, 4 weeks off
- 100mg vial at 2mg/day = 28 days of use (56mg; a mixed vial keeps 4 weeks)
- Results start showing at weeks 3–4, significant at weeks 6–8
- Most popular setup: 100mg vial + 2mL BAC water = 50mg/mL concentration
- Free calculator: Reconstitution Calculator →
The standard injectable GHK-Cu dose is 1–2mg per day, subcutaneously. Most people start at 1mg and increase to 2mg after week 1–2. For topical use, standard concentration is 2–4% applied once or twice daily. Full protocol below.
The dosing below is built around the 100mg vial Ascension stocks, which is the size nearly every GHK-Cu protocol is written for.
GHK-Cu Injectable Dosage
When reconstituting a 100mg vial, the amount of BAC water you add determines your concentration and how many units you draw per dose. The table below covers the most common setups:
The 2mL setup (50mg/mL) is the most popular — easy math, manageable injection volumes, and fits well with standard insulin syringes.
Protocol 1 — Skin & Anti-Aging
- Dose: 1–2mg per injection
- Frequency: Once daily (morning preferred)
- Duration: 8–12 weeks
- Best for: Collagen production, skin elasticity, anti-aging
- Expected results: Visible at weeks 4–6
Protocol 2 — Wound Healing & Recovery
- Dose: 2mg per injection
- Frequency: Twice daily (morning + evening)
- Duration: 4–8 weeks or until healed
- Best for: Post-procedure recovery, chronic wounds, inflammation
Protocol 3 — Hair Growth
- Dose: 1mg injectable daily + topical GHK-Cu on scalp
- Frequency: Daily
- Duration: 12–16 weeks minimum (hair cycles are slow)
- Note: Don't expect visible results before week 8 — hair follicle turnover takes time
Protocol 4 — Maintenance After Cycle
- Dose: 1mg every other day or 3x per week
- Use this: After completing an 8–12 week cycle
- Why: Maintains benefits while allowing receptor sensitivity to reset
How long does a 100mg vial last? It depends on your dose and frequency:
GHK-Cu Topical Dosage
Most commercial GHK-Cu serums come in the 2–4% concentration range — that's the target. Higher isn't better; what matters is getting it on consistently.
- Standard concentration: 2–4%
- Application amount: 3–6 drops per area, fingertip application
- Frequency: Once or twice daily — morning and/or evening
- Timing: After cleansing, before moisturizer
Amount by area:
- Face: 3–5 drops
- Neck/décolletage: 5–8 drops
- Scalp (hair growth): 8–10 drops massaged in, leave on
Injectable vs topical — which one do you actually need?
Cycle Length & When to Take a Break
Standard cycle: 8–12 weeks on, 4 weeks off.
Why cycle at all? GHK-Cu receptor sensitivity may gradually reduce with continuous use. A 4-week break resets this. After the break, restart at your starting dose — you don't need to ramp up as slowly as the first time.
Some people run longer cycles (16–20 weeks) without issues. It's not dangerous, it's precautionary. If you're using the KLOW blend (GHK-Cu + BPC-157 + TB-500 + KPV), follow the same 8–12 week cycle.
GHK-Cu Dosage by Goal
What Affects Your Results
- Quality of GHK-Cu — purity matters. Use vendors with third-party COA (≥98% purity). Lower purity = weaker effect and more unknowns.
- Consistency — GHK-Cu works through cumulative collagen remodeling. Missing doses disrupts the process. Daily is better than sporadic.
- Topical vs injectable synergy — combining both (injectable systemically, topical on target area) produces better results than either alone. More signal to the tissue.
- Diet — adequate protein intake supports the collagen synthesis that GHK-Cu stimulates. Skimping on protein limits how much you get out of the peptide.
- Starting point — people with more visible aging or skin damage often see faster apparent results. Not because GHK-Cu works harder, but because there's more room for visible improvement.
Frequently Asked Questions
The information in this article is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any new supplement or compound. Results vary by individual.