MOTS-c Dosage Chart.
MOTS-c is a mitochondrial-derived peptide that supports metabolic health, fat loss, and exercise performance. Here are the most commonly used dosing protocols.
Half-Life
~12 hours
Injection
Subcutaneous
Best Timing
AM, fasted
Storage
2 – 8 °C
Dosage Protocols
Dose per injection, frequency, and total weekly amount across experience levels.
Syringe units assume a 10 mg vial mixed with 1 mL of bacteriostatic water (10 mg/mL). Use the calculator below for your exact setup.
5 mg
per injection · 50 units
Frequency
3× / week
Weekly Total
15 mg
Cycle Length
4 – 8 weeks
15 mg/wk
10 mg
per injection · 100 units
Frequency
3× / week
Weekly Total
30 mg
Cycle Length
8 – 12 weeks
30 mg/wk
10 – 15 mg
per injection · 100 units
Frequency
5× / week
Weekly Total
50 – 75 mg
Cycle Length
12 – 16 weeks
50 – 75 mg/wk
Weekly Schedule
Suggested injection days for each protocol. Space doses evenly throughout the week.
| Day | Mon | Tue | Wed | Thu | Fri | Sat | Sun |
|---|---|---|---|---|---|---|---|
| beginner | |||||||
| intermediate | |||||||
| advanced |
Reconstitution Calculator
Enter your vial size, how much water you added, and the dose you want — we'll tell you exactly how much to draw.
Standard insulin syringe
Concentration
5.00 mg/mL
Draw volume
1.00 mL
= 5 mg ÷ 5.00 mg/mL
Units to draw (1 mL syringe)
100 units
1 mL Syringe
100 IUTips & Notes
Timing
Inject in the morning on an empty stomach. MOTS-c works best in a fasted state when AMPK activation is highest.
Cycling
Run 4 – 8 week cycles followed by a 4-week break. Long-term continuous use is not well understood yet.
Stacking
Commonly paired with 5-Amino-1MQ or other metabolic peptides. Avoid combining with other compounds that heavily target AMPK without guidance.
Storage
Keep unreconstituted vials in the fridge (2 – 8 °C). After mixing, refrigerate and use within 3 – 4 weeks. Never freeze the mixed solution.
Disclaimer: This content is for informational purposes only. Always consult a qualified healthcare professional before starting any new peptide protocol. PeptideDeck is not responsible for individual use.