Dosing Guide

KPV Dosage Chart & Schedule Guide.

KPV (Lys-Pro-Val) is an anti-inflammatory tripeptide derived from alpha-MSH that inhibits NF-κB signaling. It is used for gut inflammation, IBD support, and systemic anti-inflammatory effects via subcutaneous injection or oral capsules.

Half-Life

~4 – 6 hrs

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Injection

SubQ or Oral

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Best Timing

AM (empty stomach)

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Storage

2 – 8 °C

Dosage Protocols

Dose per injection, frequency, and total weekly amount across experience levels.

Syringe units assume a 5 mg vial mixed with 2 mL of bacteriostatic water (2.5 mg/mL). Use the calculator below for your exact setup.

Beginner

200 mcg (0.2 mg)

per injection · 8 units

Frequency

1× / day · 5 days/wk

Weekly Total

1 mg

Cycle Length

4 – 8 weeks

Intermediate

300 mcg (0.3 mg)

per injection · 12 units

Frequency

1× / day · 5 days/wk

Weekly Total

1.5 mg

Cycle Length

8 – 12 weeks

Advanced

500 mcg (0.5 mg)

per injection · 20 units

Frequency

1–2× / day · 5 days/wk

Weekly Total

2.5 – 5 mg

Cycle Length

8 – 12 weeks

Weekly Schedule

Suggested injection days for each protocol. Space doses evenly throughout the week.

DayMonTueWedThuFriSatSun
beginner
intermediate
advanced

KPV Reconstitution Calculator

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Standard insulin syringe

Concentration

2.50 mg/mL

Draw volume

0.08 mL

= 0.2 mg ÷ 2.50 mg/mL

Units to draw (1 mL syringe)

8 units

1 mL Syringe

8 IU
020406080100 IU

Tips & Notes

Timing

Inject subcutaneously in the morning on an empty stomach. For twice-daily advanced protocols, space doses 12 hours apart (morning and evening). Oral capsules should also be taken on an empty stomach.

Cycling

Run 4–8 week cycles with 2–4 week breaks. For chronic gut conditions, extend to 8–12 weeks. KPV has lower desensitization risk than many peptides, but cycling is still recommended.

Stacking

The KPV + BPC-157 combination is the most popular gut-healing stack. KPV suppresses inflammation (NF-κB inhibition) while BPC-157 repairs mucosal tissue. Dose BPC-157 at 250–500 mcg alongside KPV.

Storage

Store lyophilized vials at -20 °C for long-term stability. After reconstitution with bacteriostatic water, refrigerate at 2–8 °C and use within 3–4 weeks. A 5 mg vial at 200 mcg/day lasts ~25 days.

Disclaimer: This content is for informational purposes only. Always consult a qualified healthcare professional before starting any new peptide protocol. PeptideDeck is not responsible for individual use.

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