Dosing Guide

Enclomiphene Dosage Chart & Bloodwork Guide.

Enclomiphene is a selective estrogen receptor modulator (SERM) that blocks pituitary estrogen receptors, increasing LH and FSH to stimulate natural testosterone production while preserving fertility and sperm production.

Half-Life

~7 – 10 hrs

💊

Route

Oral

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Best Timing

AM

🏠

Storage

Room temp

Dosage Protocols

Dose per day, frequency, and total weekly amount across dosing tiers.

Conservative

6.25 mg

Oral capsule

Frequency

1× / day

Weekly Total

43.75 mg

Cycle Length

4 – 6 weeks

Standard

12.5 mg

Oral capsule

Frequency

1× / day

Weekly Total

87.5 mg

Cycle Length

6 – 12 weeks

Full

25 mg

Oral capsule

Frequency

1× / day

Weekly Total

175 mg

Cycle Length

6 – 12 weeks

Weekly Schedule

Enclomiphene is taken daily. All tiers follow the same 7-days-on schedule.

DayMonTueWedThuFriSatSun
conservative
standard
full

Recommended Bloodwork

  • Baseline (before starting): Total Testosterone, Free Testosterone, Estradiol (sensitive), LH, FSH, SHBG, Prolactin, CBC, CMP with liver enzymes
  • Follow-up (weeks 4 – 6): Total Testosterone, Free Testosterone, Estradiol (sensitive), LH, FSH
  • Ongoing (every 8 – 12 weeks): Full panel repeat

Tips & Notes

Timing

Take once daily at the same time each morning with or without food. Morning dosing aligns with natural testosterone rhythm and allows accurate morning bloodwork.

Cycling

Effects begin within 2 weeks and plateau by week 4. Standard cycles are 6 – 12 weeks. Some clinicians prescribe long-term for secondary hypogonadism. Start at 6.25 mg and titrate up based on bloodwork.

Stacking

Sometimes combined with Kisspeptin-10 (works upstream at the hypothalamus) or low-dose anastrozole if estradiol rises excessively. Monitor E2 levels before adding an AI.

Storage

Store at room temperature (20 – 25 °C / 68 – 77 °F). Protect from light and moisture. Shelf life up to 24 months when stored properly.

Disclaimer: This content is for informational purposes only. Always consult a qualified healthcare professional before starting any new protocol. PeptideDeck is not responsible for individual use.

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