Wegovy Dosage Chart & Titration Schedule.
Wegovy (semaglutide 2.4 mg) is a GLP-1 receptor agonist approved for chronic weight management in adults. It follows a gradual 5-step titration over 16 weeks to reach the 2.4 mg maintenance dose and minimize gastrointestinal side effects.
Half-Life
~1 week
Injection
Subcutaneous
Frequency
Once weekly
Storage
2 – 8 °C
Titration Schedule
Standard dose escalation from 0.25 mg to the 2.4 mg maintenance dose over 16 weeks. If 2.4 mg is not tolerated, 1.7 mg may be used as the maintenance dose.
Vials vary in concentration. Use the calculator below to find your exact draw volume.
0.25 mg
per injection · Weeks 1 – 4
Frequency
1× / week
Monthly Total
1.0 mg
Purpose
GI tolerance
0.25 mg/wk
0.5 mg
per injection · Weeks 5 – 8
Frequency
1× / week
Monthly Total
2.0 mg
Purpose
First therapeutic dose
0.5 mg/wk
1.0 mg
per injection · Weeks 9 – 12
Frequency
1× / week
Monthly Total
4.0 mg
Purpose
Continued escalation
1.0 mg/wk
1.7 mg
per injection · Weeks 13 – 16
Frequency
1× / week
Monthly Total
6.8 mg
Purpose
High-dose escalation
1.7 mg/wk
2.4 mg
per injection · Week 17+
Frequency
1× / week
Monthly Total
9.6 mg
Purpose
Maintenance dose
2.4 mg/wk
Pick Your Injection Day
Wegovy is injected once per week on the same day. Choose whichever day fits your routine best and stick to it.
| Day | Mon | Tue | Wed | Thu | Fri | Sat | Sun |
|---|---|---|---|---|---|---|---|
| Option A | |||||||
| Option B | |||||||
| Option C |
Compounded Semaglutide Reconstitution Calculator
For compounded semaglutide vials — enter your vial size, how much bacteriostatic water you added, and your target dose to find the exact draw volume.
Double-click a preset to edit it
Double-click a preset to edit it
Double-click a preset to edit it
Standard insulin syringe
Concentration
1.00 mg/mL
Draw volume
0.250 mL
= 0.25 mg ÷ 1.00 mg/mL
Units to draw (1 mL syringe)
25 units
1 mL Syringe
25 IUTips & Notes
Timing & Consistency
Inject on the same day each week at any time of day, with or without food. Missed dose: if 5 days or fewer have passed since the missed dose, inject as soon as possible. If more than 5 days have passed, skip it and resume your normal schedule the following week.
Injection Sites
Inject subcutaneously into the abdomen (at least 2 inches from the navel), front of the thigh, or upper arm. Rotate injection sites each week to prevent irritation and lipodystrophy.
Managing Side Effects
Nausea, vomiting, diarrhea, and abdominal pain are most common during dose escalation. If GI side effects are poorly tolerated, stay at the current dose for an additional 4 weeks before increasing. Do not skip titration steps.
Storage
Store Wegovy pens at 2 – 8 °C in the refrigerator. Pens may be kept at room temperature (≤30 °C) for up to 28 days. Never freeze. For compounded semaglutide vials, keep refrigerated and use within 28 days of reconstitution.
Disclaimer: Wegovy (semaglutide) is an FDA-approved prescription medication — it must be prescribed and supervised by a licensed healthcare provider. Compounded semaglutide is not FDA-approved. Always consult a qualified physician before starting, adjusting, or stopping any treatment. PeptideDeck is not responsible for individual use.