-15%VIP Spray
VIP (Vasoactive Intestinal Peptide) · 10mL Nasal Spray · Limitless Life Nootropics
Price with PeptideDeck coupon applied at checkout
PeptideDeck
≥98% Purity
Third-party verified
10mL Spray
Nasal delivery
GMP Compliant
USA manufactured
28 Amino Acids
Neuropeptide
About VIP Spray
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide with broad physiological roles including immune regulation, vasodilation, and neuroprotection. It has gained particular attention in CIRS (Chronic Inflammatory Response Syndrome) research and is delivered nasally for direct systemic and CNS effects.
Product Specifications
Key Benefits
Anti-Inflammatory & Immune Regulation
VIP modulates immune cell function and balances Th1/Th2 responses, making it a key peptide in research on chronic inflammatory conditions and immune dysregulation.
Neuroprotection
VIP acts on VPAC receptors in the central nervous system to support neuronal survival, reduce neuroinflammation, and promote healthy brain function.
Pulmonary & Respiratory Support
VIP promotes pulmonary surfactant production and supports healthy lung function, with particular relevance in research on pulmonary hypertension and respiratory conditions.
Circadian Rhythm Regulation
VIP plays a critical role in the suprachiasmatic nucleus (SCN), the brain's master clock, helping to regulate circadian rhythms and sleep-wake cycles.
Vasodilation & Blood Flow
As its name suggests, VIP is a potent vasodilator that relaxes smooth muscle in blood vessels, promoting healthy blood flow and cardiovascular function.
Frequently Asked Questions
What is VIP?
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide with broad physiological roles including immune regulation, vasodilation, neuroprotection, and circadian rhythm control. It is naturally produced throughout the body, with highest concentrations in the gut and nervous system.
How is VIP used in CIRS research?
VIP has gained significant attention in Chronic Inflammatory Response Syndrome (CIRS) research, where it is studied for its ability to regulate immune function, reduce inflammatory markers, and restore normal physiological responses in patients with biotoxin-related illness.
Why nasal delivery for VIP?
Nasal delivery is the preferred route for VIP because it enables rapid absorption through the nasal mucosa, providing both systemic and direct CNS effects. This bypasses first-pass liver metabolism and offers a non-invasive, needle-free administration method.
How should VIP spray be stored?
Store in a cool, dry place away from direct sunlight. Refrigeration is recommended to maximize shelf life and maintain peptide stability. Keep the bottle tightly sealed when not in use.
What conditions is VIP researched for?
VIP is actively researched for CIRS (Chronic Inflammatory Response Syndrome), pulmonary arterial hypertension, neurodegenerative conditions, inflammatory bowel disease, circadian rhythm disorders, and various autoimmune conditions. It remains a research peptide and is not approved for treatment of any specific condition.
How VIP Works
VIP activates two G-protein coupled receptors: VPAC1 and VPAC2. These receptors are distributed throughout the body, including the lungs, gut, immune cells, and central nervous system, enabling VIP’s wide-ranging physiological effects.
Upon receptor binding, VIP stimulates cyclic AMP (cAMP) signaling, which modulates immune cell function by shifting the Th1/Th2 balance, reducing pro-inflammatory cytokine production, and promoting regulatory T cell activity. This makes VIP a powerful immune modulator.
VIP also promotes vasodilation through smooth muscle relaxation, supports pulmonary surfactant production for healthy lung function, and regulates circadian neurons in the suprachiasmatic nucleus (SCN). Nasal delivery provides both systemic and direct CNS access for these neuroimmune effects.