-15%5-Amino-1MQ Capsules
50mg per capsule · 60 capsules · NNMT Inhibitor · Limitless Life Nootropics
Price with PeptideDeck coupon applied at checkout
PeptideDeck
≥98% Purity
Third-party verified
60 Capsules
50mg each
GMP Compliant
USA manufactured
NNMT Inhibitor
Selective mechanism
About 5-Amino-1MQ
5-Amino-1MQ is a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). Unlike traditional peptides, it is a small molecule (quinolinium derivative) that works at the enzymatic level within fat cells. By inhibiting NNMT, it redirects nicotinamide into the NAD⁺ salvage pathway, boosting cellular energy metabolism while conserving SAM — the universal methyl donor critical for epigenetic regulation.
Product Specifications
Recommended Dosage
Key Benefits
Fat Loss & Body Composition
5-Amino-1MQ reduces body weight and shrinks fat cells without affecting food intake or lean muscle mass. It targets fat metabolism at the cellular level for cleaner body recomposition.
NAD⁺ Boost & Cellular Energy
By redirecting nicotinamide into the NAD⁺ salvage pathway, 5-Amino-1MQ increases intracellular NAD⁺ — critical for mitochondrial function, DNA repair, and sirtuin activation.
Metabolic Support & Insulin Sensitivity
NNMT inhibition improves glucose tolerance and insulin sensitivity, helping address hyperglycemia, dyslipidemia, and visceral adiposity for better overall metabolic health.
Cellular Health & Tumor Defense
NNMT is overexpressed in several cancers. Inhibiting it with 5-Amino-1MQ modulates tumor cell metabolism and reduces proliferation, supporting cellular defense mechanisms.
Anti-Aging & Longevity
NNMT inhibition boosts NAD⁺ (activating sirtuins) and preserves SAM (supporting methylation) — two major longevity pathways that counteract epigenetic drift and mitochondrial decline.
How 5-Amino-1MQ Works
5-Amino-1MQ inhibits NNMT, an enzyme highly expressed in white adipose tissue that catalyzes the methylation of nicotinamide using SAM as a methyl donor. By blocking this enzyme, two important things happen simultaneously.
First, nicotinamide is redirected into the NAD⁺ salvage pathway, increasing intracellular NAD⁺ concentrations. NAD⁺ is essential for cellular energy metabolism, DNA repair, and sirtuin activation — a family of enzymes involved in longevity and metabolic regulation.
Second, SAM (the universal methyl donor) is conserved, supporting healthy methylation reactions throughout the body including epigenetic regulation. In fat cells specifically, this shifts energy balance from storage to utilization, shrinking adipocytes and reducing lipid accumulation without affecting food intake.
Frequently Asked Questions
Is 5-Amino-1MQ actually a peptide?
No. Despite being sold alongside peptides, 5-Amino-1MQ is a small molecule (a quinolinium derivative), not a peptide. It does not consist of amino acid chains. It is grouped with peptides commercially because it appeals to the same health-optimization community.
How does 5-Amino-1MQ differ from other fat-loss compounds?
Unlike stimulant-based compounds that work through the sympathetic nervous system, 5-Amino-1MQ works at the enzymatic level within fat cells by inhibiting NNMT. It does not increase heart rate, blood pressure, or CNS stimulation, and does not suppress appetite.
Can 5-Amino-1MQ be combined with NMN or NR?
Yes, 5-Amino-1MQ works through a complementary mechanism to direct NAD⁺ precursors. While NMN and NR provide substrate for NAD⁺ synthesis, 5-Amino-1MQ prevents the NNMT enzyme from diverting nicotinamide away from NAD⁺ production. Stacking them can maximize NAD⁺ levels.
What side effects should I be aware of?
5-Amino-1MQ is generally well tolerated. It does not reduce food intake and does not cause loss of lean muscle mass. Most users report no noticeable side effects at standard doses. As with any supplement, start with the lowest effective dose and monitor how your body responds.
How should 5-Amino-1MQ capsules be stored?
Store at room temperature (15–25°C) for short-term use. For long-term storage, refrigerate at 2–8°C. Protect from direct light and moisture. Keep container tightly sealed.